Covid-19 magnetizer or coronavirus disease
New information on COVID-19
“Viruses that mutate a lot, such as COVID and HIV, make the vaccine's efficacy temporary, in the more or less short term. New vaccine failure against the AIDS virus. It has been 30 years since all attempts at an HIV vaccine have failed. The latest failure is that of Johnson Johnson, who uses technology identical to that used for his vaccine against COVID. After 2 years of hindsight, they know that the protection is only 25%. (2021)
Against Covid-19, there would be an alternative to vaccination, faster to develop and easier to implement: the lure.
The principle: to fix the virus on decoys from which it can no longer be released, which prevents it from infecting cells. Subsequently, it is eliminated naturally by the body.
These decoys are small proteins (peptides) that mimic ACE2. They do not elicit immune reactions and are not biologically toxic.
COVID-19 has a stronger affinity for them than with human cells.
Their administration could be done as a preventive measure in the form of a nasal spray and therapeutic via sublingual tablets which would line the mucous membranes of the upper airways.
The extraordinary situation of this multitude of vaccine candidates under study increases the need for volunteers to test the tolerance and efficacy of these vaccines. So far, none of the clinical studies initiated have involved French patients.
Since Thursday 1/10/2020, any French adult who wishes can register online to participate in phase 2 and 3 clinical trials on the platform https://www.covireivac.fr.
There is no age limit or health prerequisites. The goal, on the contrary, is to recruit various profiles especially vulnerable to the coronavirus.Even people who have already had Covid-19 can also participate. Volunteers from the most affected regions will likely be privileged, because they must be exposed to the virus in their daily lives to measure the effectiveness of the vaccine.
As always, trial participants are not guaranteed to receive the vaccines. Some will have placebo injections without reporting it to avoid interpretation bias, they are control individuals. As for the risk incurred ...
The goal is to identify several thousand volunteers, receiving an allowance to compensate them for the time and constraints suffered in order to achieve:
5 phase 2 trials with around 100 participants each. They aim to estimate the optimal dose of treatment, measure the immune response and verify the safety of the injection;
3 phase 3 trials with thousands of individuals. They assess the protection of the vaccine in real life. Last step before the marketing request.
The first tests should start in France at the beginning of 2021. The challenge of the initiative is twofold: they allow French scientists to stay in the race and advance international research.
24 clinical investigation centers will be spread over the territory. They will welcome the volunteers for the injections and the accompanying medical follow-up.
List of questions and answers on the Covid
Covid-19, the track of monoclonal antibodies
The intensity of the pandemic is in full swing in Latin America and appears to be rebounding in Asia.
One question is prominent: How long has the immunity conferred on the 8 million (8,884,000) people worldwide who to date (June 21, 2020) have survived after contacting Covid-19 (465,000 are died in 196 countries and territories) will it last? Can they be contaminated again? If the answer is no, how do you make a vaccine profitable ?
How does immunity work?
Immunity consist of 2 main categories:
1) The innate is the body's first line of defense made up of physical barriers which are:
skin and mucous membranes;
mucus and secretions;
white neutrophil cells and macrophages - our infantry cells;
cytokines stimulate the immune system.
2) The adaptive Whose role is to protect the organism in case an organism attacks it again. It consists of 2 forms which complement each other:
humoral produces immunoglobulins (antibodies) that neutralize infection by using B cells;
the cell uses T cells which are made up of CD8 + (their job to destroy infected cells) and CD4 + to coordinate and direct CD8 + attacks.
How long is the immunity?
The duration of adaptive immunity after infection with a coronavirus is highly variable.
For the SARS-CoV pandemic, in 2002-2004, very aggressive, but fortunately of small magnitude, there were 8,096 infected in 30 countries and 774 deaths. The antibodies of the survivors persisted for about 3 years. In contrast, the antibodies linked to the coronaviruses responsible for mild colds persist only for a few months.
In the case of Covid-19, the antibodies would become weakly neutralizing after a delay of 3 weeks to 3 months.
Serological tests only relate to the presence or absence of antibodies (humoral immunity). These tests have a lot of false negatives, so their reliability is far from perfect.
Is there hope for an end to the Covid-19 epidemic?
The good news would be the existence of cross immunities: Old coronavirus infections such as simple colds would have the capacity to protect a significant part of the population against Covid-19. There would be group immunity reached faster than expected, causing the epidemic to end. This is thanks to the presence of CD8 + and CD4 + directed against the Spike protein. The virus uses this protein to enter cells.
What are the risks of recontamination with Covid-19?
At the moment we often talk about the risk of recontamination in the short term,
but there is no hard evidence to support this idea yet.
Can Covid-19 stay in the body?
Viruses that can remain latent in the body in cell reservoirs are DNA viruses,
while Covid-19 is an RNA virus, the answer is no.
Who is the target of Covid-19?
The virus targets the ACE2 receptor to enter human cells. It has been identified 14 antibodies which neutralize this receptor, BD-368-2 would be the most powerful. Studies will begin in humans. This monoclonal antibody could be available from next winter and be given as a preventive and curative measure.
What treatment against Covid-19?
The monoclonal antibody (BD-368-2) could be available from next winter and be given as a preventive and curative measure. It could be produced on a large scale and allow the wait, within 12 to 24 months, of a vaccine conferring cellular and humoral immunity or one of the two. There is also the technique of injecting plasma from cured people which is not applicable everywhere, although it seems to work.
Does the virus mutate?
Since its emergence more than 30 mutations of the virus have been identified.
Highly contagious agents try by this natural process to strengthen themselves to become more resistant and more aggressive when they multiply.
Their behavior only changes for certain mutations.
The D614G mutation would increase the contagiousness and speed of reproduction of the virus. By its progression, it could become the dominant strain. It affects the Spike protein that Sars-CoV-2 uses to infect human cells.
How effective will the vaccine be?
We have every right to be concerned about the efficacy of the vaccine for 2021, as many vaccine projects have only taken the initial Wuhan strain as a reference and have found the Sars-CoV-2 mutation unlikely in the short term.
Is the pandemic spreading?
In Europe it is weakening, but while the number of new cases worldwide was 100,000 two months after the start of the epidemic, we are now at 100,000 new cases per day.
The African continent, very spared so far, sees the spread of the disease mainly in 3 countries: Nigeria, Sudan and South Africa.
Bombay and New Delhi are densely populated cities with overcrowded intensive care units.
Rural residents stranded in cities were allowed to return home, which allowed the virus to spread to rural areas and to towns in Indian states crossed by these special trains.
India has 410,461 cases and 13,251 deaths, although these figures are rising sharply, they remain lower than France, although this country has 1.4 billion inhabitants.
The epidemic in the United States with its 2,311,345 cases and 121,609 deaths:
the epidemic would have crossed its peak and would begin to decrease with a drop in daily deaths, with a shift from the epicenter of New York to the states of south, west and center.
On the other hand, in Latin America and mainly in Brazil the situation is very worrying where the population is not confined and the announcements on the deaths are occasional.
Is there the risk of a second wave?
There were 3 rebounds where the epidemic had already passed: in early May in Singapore for construction workers, in late May in Seoul for a hundred people infected in a nightclub and the last in Beijing where 158 people were infected. at the Xin Fadi wholesale market.
The danger comes from asymptomatic subjects who are difficult to detect.
There are many who think that by the fall and next winter more rebounds will occur, so why be so lax in this context?
Covid-19: workers at risk
The deconfinement protocol which relaxed the health rules in companies provides that people at risk of severe form of Covid-19 can remain telework until August 31, 2020. If it is impossible to exercise their profession remotely, they benefit the extension until this date of the simplified work stoppage system.
Covid-19: blood circulation
After the airway cells, Sars-CoV-2 particularly attacks those of the vessels.
Early or not taking an anticoagulant?
It appears obvious that the vascular, arterial and venous lesions that it induces are the source of serious forms and of fatal cases. These lesions result in pulmonary emboli or organ, heart, brain and kidney failure. The creation of multiple microthromboses in the pulmonary vessels prevents many patients from being well ventilated and die.
Arterial, aortic, carotid, cerebral, renal and digestive damage has been observed. People with healthy arteries have had unusual myocardial infarctions due to coronary thrombosis, sometimes with complications from heart failure and death.
The occlusion of millimeter-sized vessels causes micro-frostbite.
Prevention by anticoagulant does not seem sufficient. It is also useful to administer in intensive care a strong anticoagulation and not only preventive.
Why these thromboses?
Any infection favors the occurrence of venous thrombosis, but the vascular tropism of Sars-CoV-2 goes far beyond. The virus directly attacks the arteries and veins. It specifically targets so-called endothelial cells which form a layer in permanent contact with the blood and which reacts with all circulating elements.
These cells are equipped with the ACE2 receptor used by the virus to enter human cells.
The viral load period lasts 5 to 7 days, and if the body's immune defense reaction is too violent, massive activation of macrophage cells, this creates major lesions where the viruses reside in the lungs and blood vessels in particular. Damaged endothelial cells cause more or less diffuse coagulation disorders (thrombosis). This concerns vessels of any caliber and anywhere in the body.
Vascular inflammation 2 theories:
The first, the infection is initially pulmonary and thromboses are only one mechanism among others. The proof is not constant in all patients.
The second, and the conclusion of the autopsies on deceased patients which show a diffuse coagulation of the small arterial vessels which border the pulmonary alveoli, an endothelium everywhere damaged or modified. In this case, at the start of infection, the systematic intake of an anticoagulant at a preventive dose would be fully justified.
Why do young people and non-young people refuse to wear the mask?
In both cases, it is selfishness that governs them. Younger people mistakenly think that they risk nothing, that their children did not risk anything either and that if older people die of their faults they do not bother at all. As for the older ones, they assume that they have lived well and as long as they are not sick it does not matter and their grandchildren are not at risk.
It would be time to show sociability, responsibility, respectability and fraternity towards others in this area as well as others, everyone would in reality be a winner. The following 2 pieces of information may help to make the right behavior choices:
Seasonal coronavirus infection does not protect against infection with the Sars-CoV-2 virus and other related illnesses, such as Kawasaki disease syndrome. Children and young adults are not protected.
Although it is true that people of a certain age were initially injected with deadly sedatives to make room for the younger ones, what would happen if there were too many sick young adults? At the same time, would that happen with the coin toss system? To avoid this choice, maybe it's time to respect yourself and others.
Contaminated mink slaughtered in the Netherlands
In 20 farms, cases of mink contaminated with Covid-19 lead to the slaughter of tens of thousands of these mammals. The slaughter of the last 12,000 mothers, from the last farm, took place on Monday 12/7/2020 and 2 livestock workers reportedly contacted the Covid-19 via mink.
Fewer drugs against Covid-19
Discovery and Solidarity (European clinical trials) discontinued ritonavir / lopinavir treatment on suspicion of side effects and considered ineffective.
The 2 trials now only focus on remdesivir. Within the EU, conditional placing on the market has just been obtained.
The WHO has endorsed the discontinuation of hydroxychloroquine.
UV-C and Covid-19
UV-C ultraviolet rays are present in solar radiation and have a shorter wavelength than visible light. They are harmful to the skin, but fortunately filtered by the ozone layer.
They kill 90 to 99% of bacteria and viruses depending on time of exposure and distance.
Tests have also shown that, if the influenza virus is destroyed with radiation of 6 megajoules, the Covid-19 is resistant to radiation of 70 megajoules.
The sale to individuals of UV-C radiation devices is prohibited.
For professionals, there is for example the Deeplight (Deliled). A robot that costs 2,000 € and which eliminates germs from an enclosed space in 30 minutes for a 20 m2 room.
51 tests have been validated, the list can be found on:
Https://covid-19.sante.gouv.fr/tests, but they do not all offer the same finesse of detection and, worse, some manufacturers have only had their tests validated once, allowing not monitoring the quality of industrial production. Their purchase price varies from 5 to 12 €.
Pharmacies, since July 11, 2020, have been authorized to perform rapid diagnostic orientation tests (TROD). These serological tests are carried out from a sample of a drop of blood put in contact with a strip containing an antigen recognizing the presence of antibodies against Covid. In a few minutes, the result appears allowing to know if one has made antibodies and indicates a past infection.
If the test is positive, the person who has been infected with Sars-CoV-2 will be asked to go to a medical laboratory for a serological test to confirm the Trod result and a PCR, as it is important to know if she is still carrying the virus. The latter 2 are reimbursed if there is a medical prescription.
The price of the Trod test is between 20 and 25 € not refunded. For information, the price for a complete laboratory test is 45 €.
Besides the fact that these tests generate a certain number of false positives, it is believed that antibodies have developed, but this is not the case and false negatives, antibodies that one possesses are not detected; You should not let your guard down prematurely, even with positive results, as it is far from certain that immune protection is effective against reinfection. And there is no evidence that one cannot shed the virus again even without being sick oneself.
The rapid detection test (RDT) carried out by a medical biologist, the rapid diagnostic orientation test (TROD) carried out by another health professional in his pharmacy or practice and the self-test carried out by the patient himself ( prohibited for sale by the Haute Autorité de santé!) are identical products except for possible subtle changes in design.
The price framework for single-use masks as well as hydroalcoholic gels and solutions is extended until January 10, 2021, when it was initially due to expire with the end of the state of health emergency.
Occupational disease and Covid-19
Recognition as an occupational disease allows 100% coverage of care, but also more favorable coverage of daily allowances,
as well as the annuity allowance or capital in the event of permanent incapacity and finally a annuity paid to beneficiaries in the event of death.
Facilitated procedures: all caregivers in medico-social and health establishments, non-nursing staff working in face-to-face in these structures as well as people providing support and transport for patients and private health professionals suffering from a severe form of COVID - 19 (need for oxygen therapy) will have their disease automatically and systematically recognized as an occupational disease.
For non-caregivers, recognition will be facilitated, the regional committees will be replaced by a single national recognition committee dedicated to Covid-19 and will ensure the homogeneity of the processing of requests. No degree of permanent disability will be required under this simplified procedure.
First case of intrauterine contamination
The first confirmed case of intrauterine contamination with Covid-19 arrived in March 2020.
The newborn male suffered from neurological symptoms associated with Covid-19.
It can occur by transmission from mother to fetus via the placenta in the last weeks of pregnancy but it is very rare.
No more than 2% of children born to mothers with Covid-19 have tested positive for the virus and even fewer developed severe symptoms.
It is known that the loss of smell can be linked to viral respiratory infections.
The mechanisms are not yet very clear: a swelling of the nasal mucosa would close the olfactory feint blocking the transmission of odors to the brain; the virus would invade the central nervous system and the olfactory bulb (MRIs would have shown damage to this olfactory bulb); the virus may not directly infect olfactory neurons, but support cells rich in ACE2 receptors causing massive loss of olfactory neurons.
50% of patients recover their sense of smell within 15 days, 35% within 2 months and 15% for whom it is longer.
Stem cells, present in the nose, allow olfactory neurons to regenerate, but for optimal functioning they need olfactory rehabilitation. Just breathe 7 simple and different smells 3 times a day.
It is likely that this intense inflammatory reaction causing the loss of smell is the body's response to prevent the virus from spreading to the rest of the body and thus protect the lungs. This would explain why in severe, even critical forms (acute respiratory distress syndrome), only 7% of patients have anosmia. For moderate forms (pneumonia), we find 4.5% and for mild forms the percentage rises to 85%.
Does wearing prescription glasses protect against Covid-19?
Wearing glasses is a little extra.
There are 2 potential routes of eye infection:
The conjunctival way. It is known that in the conjunctiva, the ocular mucosa, there are receptors for the virus.
The tear duct. When contaminated tears flow into the nasal passages, they affect the airways.
10% of patients with Covid-19 would present with eye manifestations of the disease (conjunctivitis).
Eye protection: glasses, visors or face shields have a dual role, they protect against infectious droplets
and they prevent their wearers from touching the eyes (this gesture is repeated unconsciously about ten times per hour).
It is recommended to wear protective glasses which are much wider than prescription glasses which are not sufficient.
As this route of contamination remains secondary, it is necessary to put on protective goggles when necessary without wearing them all the time.
Rapid antigenic tests deliver a result in less than 30 minutes (Price: 10 €)
By looking for a virus protein, they are well suited to mass screening and allow sorting in the population between negative or not very contagious subjects and very contagious subjects that they identify.
Question: of the three tests best evaluated by AP-HP, two are from French SMEs, the firm AAZ, and Biosynex, the third, is from the American group Abbott. Where did Olivier Véran, Minister of Health, buy 5 million antigenic tests on Thursday, September 17?
These tests are not efficient enough to replace the virological PCR test.
They could miss 50% of people positive for Covid, because their sensitivity is in the order of 80% in people with symptoms for less than 3 days. This sensitivity drops to 60% after 3 days and only 40% after 8-10 days.
Sensitivity is the likelihood of getting a positive test when a person is sick, which indicates their ability to identify the viral agent.
Sensitivity should not be confused with the specificity of a test, which is its ability to distinguish, in this case, Sars-CoV-2 from another virus (95% are the requirement of the French standard).
The antigen test requires collection of cells by nasopharyngeal swab as for PCR.
It identifies the virus capsid, the protein structure that surrounds RNA, instead of identifying the virus by the presence of this nucleic acid.
Roche Diagnostic has a PCR test:
which can simultaneously detect both Sars-CoV-2 and influenza A or B viruses within 15 minutes.
The High Authority for Health has extended to asymptomatic people (after its first authorization for symptomatic patients),
the authorization of samples taken by a swab from the back of the throat (oropharyngeal), taken € 37.
Another confusion: while a decree published in the official journal on 9/16/2020 states:
Antigen testing is only prescribed for asymptomatic people and contact cases;
a positive result must be confirmed by a virological test.
The test is reserved for symptomatic people showing signs of infection with a virus seen by a doctor;
that it is not necessary to verify the result by a PCR test if it is carried out by a healthcare establishment or a medical laboratory.
Price of the spectrometer to analyze the samples: € 20,000.
LC - Thursday September 24, 2020
How to distinguish between Covid-19 and the flu
Loss of smell (anosmia) is probably "the" symptom that best differentiates Covid from the flu or the common cold.
The flu has a typical pattern of high fevers: for 3 days, fever of 40 °; drop in fever for a day; then, resumption of fever at 40 ° for another 3 days. In addition, the flu more often causes a high fever.
The absence of fever, cough, runny nose, headache or throat, fatigue rather leans in favor of a cold. The fever in case of a cold usually lasts less than 24 hours. Do not forget that it is possible to have the Covid without having a fever.
Sneezing is more a sign of a cold.
Headaches seem to be a little more frequent in the case of Covid.
Symptoms of difficult breathing, diarrhea or muscle pain point to the flu or Covid.
Usually, the bronchi are not affected during a cold.
This information is not intended to make a diagnosis.
This year, the flu shot will inevitably be put even more prominently. A vaccinated person (depending on his age,…) would hypothetically have 5 out of 10 chances of not developing the flu.
What is the percentage for an unvaccinated person?
We can hope that barrier gestures, wearing a mask and washing hands (which seems new to some people) will reduce winter infections.
Remember: Until proven otherwise, any infection should be considered a Covid infection. To continue to live normally and to say to oneself that it is not serious, it is to make take a risk to the community (health and economic). Even with the flu, isolating yourself during the symptoms is useful so as not to participate in the spread of a disease which is also dangerous.
It is also possible to distinguish influenza A or B from Sars-CoV-2 by means of a PCR test from Roche Diagnostic with a result in 15 minutes.
For or against wearing the systematic mask during childbirth?
Women, who were embarrassed to breathe with the mask and demanded to remove it, experienced confrontation with caregivers requiring them to wear the mask.
The National College of Obstetrician Gynecologists of France (CNGOF), after a long internal debate, published an opinion which indicates that for asymptomatic women, wearing a mask during childbirth remains recommended in the presence of caregivers, but cannot be imposed.
Wearing a mask can promote the resurgence of old traumas due to sexual or physical violence.
The persistence of the coronavirus on everyday surfaces.
The first thing to remember: the coronavirus is eliminated in 15 seconds, after using an 80% hydroalcoholic solution.
As the temperature drops, the lifespan of Sars-CoV-2 increases.
Important information so as not to panic after reading the following: the quantities detected would certainly not be sufficient to affect a person,
because according to research on SARS, surfaces would no longer be contaminating beyond the maximum period of 14 days, assuming that it takes a few hundred particles on a surface for it to become contaminating.
In addition, all experiments were performed with an atmosphere of 50% humidity and with no light. However, we know that high humidity degrades the virus and the absence of light prevents UV rays which also destroy the virus.
After 28 days, at 20 °, it is still on stainless steel, glass, vinyl, banknotes and plastic surfaces. The only material spared is cotton, hence the importance of washing your hands.
It should also be remembered that the coronavirus resists, on average, 9 hours on the skin in an atmosphere at 50% humidity and at 25 °. By comparison, the flu virus under the same circumstances lasts 1:48 ’.
This technology presents risks:
- it has been shown that the vector DNA can occasionally integrate into the host cell genome at random.
It cannot be ruled out that it then interacts with some of our genes and disrupts cellular mechanisms.
Unlike RNA vaccines which deposit genetic instructions in cell space without the possibility of incorporation into our genomes to be read, adenovirus vaccines, on the other hand, inject their instructions, in the form of DNA, into the nucleus of the cells.
- so-called harmless vector viruses can still affect cells where there is a dysfunction and then aggravate an ongoing disease that may or may not be ignored;
- adenovirus and RNA vaccines use a single vaccine antigen to immunize people: the spike protein. This is their main flaw in the face of a virus that produces many variants. He often mutates by constantly changing Spike.
For example, the AstraZeneca vaccine is ineffective against the South African variant. Its protection is only 22%. The reason is simple: Spike is no longer recognized by our immunity, the vaccine is useless.
The 3 vaccines using adenoviruses as an immunization vector are:
- Astra Zeneca from the University of Oxford in the UK. A study of about 17,000 people gives it a protection rate of 70%;
Vaccination of nursing staff has been suspended due to too many and too intense adverse effects in the Breton hospitals of the CHU of Brest, Rennes and Morlaix. 25% of people vaccinated have had flu-like symptoms with high fever (39 degrees) leading to work stoppages for at least 24 hours.
- Spounik V of the Gamaleya research institute in Moscow under the aegis of the Russian authorities. A study of about 20,000 people gives it a protection rate of 91.6%. With the risk of developing flu-like symptoms only in 1 in 500 vaccinated;
- Janssen Pharmaceutiqua, a subsidiary of the American laboratory Johnson and Johnson in Belgium. A study of around 43,000 people gives it a protection rate of 72%. With the risk of developing flu-like symptoms only in 1 in 500 vaccinated.
They are far from the 94% effectiveness of RNA vaccines. However, they are above the 50% efficacy which is the threshold required by drug agencies around the world.
They all use harmless adenoviruses that are used to carry genetic information to help produce the Sars-CoV-2 Spike protein. This protein would allow the immune system to identify the enemy and trigger the immune response necessary to fight against it.
These vaccines have the advantage of having a logistics that meets the need for rapid and broad vaccination with lasting storage at temperatures of 2 to 8 degrees (RNA vaccines can only be stored for a few days after being stored and transported at temperatures of minus 20 degrees for Moderna and minus 70 degrees for Pfizer).
There is no point in providing 90% protection against one mutant and only 20% against another mutant that has become dominant. As explained above, Spike is no longer recognized by our immunity. At the current rate of change, no logistics necessary for the vaccine process will be able to follow and it will be quickly overwhelmed. Without losing sight of the fact that populations risk losing the pleasure and satisfaction of repeated vaccinations.
The solution might be to revert to 'old generation' vaccines produced from whole inactivated viruses. This would allow our immune system to identify all the viral proteins instead of just one that is constantly changing, which would lengthen the duration of immunization, regardless of the modification of Spike.
The CoronaVac vaccine (Sinopharm) is Chinese and is the only vaccine of this category currently marketed in the world. On a study of 50,000 people, the results obtained are: reduction of the risk of infection by 50.3%, protecting 70% of vaccinees from infection and 100% of them from serious forms.
In addition, its tolerance is very good. It is safe, sufficiently efficient and durable with fast and simple logistics, in short: the dream!
The WHO recognized the long Covid syndrome in August 2020. Its characteristics are very varied, more or less intense and durable. Symptoms persist beyond 2 months or reappear after a lull.
Even though some of these complex patients were hospitalized with severe Covid-19, most only had mild forms. They are rather young patients (36 to 51 years old), most of them athletic. Most of them are women and 50% have allergies. The majority do not have proof of their initial infection.
All describe various disorders affecting almost all parts of the body. There are 50 different manifestations of the syndrome. At first, they were sometimes treated with antidepressants for hypochondria.
Fatigue accounts for 14% of symptoms, loss of smell or taste 12%, shortness of breath 9%, cough 6% and headaches 3%. There are also tremors of the limbs, icy hands, burning sensations in some parts of the body, chills, hair loss, rashes, digestive disturbances, extreme bedridden fatigue, disturbances in memory and joint pain without the check-ups or imaging tests revealing an abnormality. In the majority of cases, there is no trace of biological causes.
It is not uncommon for late clinical signs to appear as following the outbreak of sars in 2003 and also after chikungunya which often gives rise to fevers and joint pain in its wake. All infectious pathologies can give rise to lingering forms.
For now, there is no explanation, only possible avenues. Among them, we find the persistence of the virus in the organism, a particular genetic ground which favors an inadequate immune response which is prolonged, an inflammation of the blood vessels, the deterioration of the autonomic nervous system which controls digestion and respiration. Likewise, the researchers do not exclude the stress caused by a new disease or the sedentary lifestyle linked to confinement.
For information on a session by magnetizer, see the magnetism page.